Amy Satterthwaite scored the most runs in women's ODIs 2016 - 853 runs.
| 1. Amy Satterthwaite | 853 | - |
| 2. Meg Lanning | 758 | - |
| 3. Ellyse Perry | 663 | - |
| 4. Mignon du Preez | 641 | - |
| 5. Suzie Bates | 632 | - |
| 6. Nicole Bolton | 589 | - |
| 7. Tammy Beaumont | 579 | - |
| 8. Trisha Chetty | 506 | - |
| 9. Lizelle Lee | 494 | - |
| 10. L Winfield | 461 | - |
Amy Satterthwaite scored the most runs in women's ODIs 2016 - 853 runs. Second is Meg Lanning (758), third Ellyse Perry (663).
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