Fatima Sana took the most wickets in women's ODIs 2021 - 20 wickets.
| 1. Fatima Sana | 20 | 532 |
| 2. Anisa Mohammed | 20 | - |
| 3. Shabnim Ismail | 18 | 612 |
| 4. Hayley Matthews | 18 | - |
| 5. Kate Cross | 17 | 429 |
| 6. Sophie Ecclestone | 16 | 642 |
| 7. Anam Amin | 15 | 502 |
| 8. Jhulan Goswami | 15 | 552 |
| 9. Nashra Sandhu | 15 | 580 |
| 10. Ayabonga Khaka | 14 | 466 |
Fatima Sana took the most wickets in women's ODIs 2021 - 20 wickets. Second is Anisa Mohammed (20), third Shabnim Ismail (18).
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